Cryptococcal osteomyelitis in a clinically immune-competent child
نویسندگان
چکیده
منابع مشابه
Cryptococcal osteomyelitis in a child with a novel compound mutation of the IL12RB1 gene.
The IL-12p40/IL-12Rbeta1 and IFN-gammaR1/IFN-gammaR2/STAT1 signaling pathways are important for clearing intracellular bacteria. Genetic defects within these pathways are associated with increased susceptibility to intracellular pathogens. Among these, IL-12Rbeta1 deficiency is the most common defect and leads to infections with Salmonella and Mycobacterium spp. We report a child who presented ...
متن کاملCryptococcal osteomyelitis of the spine.
We have treated seven patients with cryptococcal spondylitis. Five presented with a neurological deficit and one was HIV-positive. Amphotericin-B and 5-flucytosine were used in five patients and ketoconazole was given orally in the remaining two. Three patients made a complete neurological recovery. Since these lesions mimic spinal tuberculosis, which is commonly seen in our environment, we dra...
متن کاملCryptococcal osteomyelitis of the skull.
An otherwise healthy 65-year-old male from a rural area presented with a 1-month old non-tender scalp mass. He had a history of being stuck with a stone in the parietal region a year earlier but hadn't developed any complications. Needle aspiration of the mass revealed numerous yeast cells, which were confirmed to be Cryptoccus neoformans. This case describes a rare presentation of C. neoforman...
متن کاملBifocal Cryptococcal Osteomyelitis in an Immunocompetent Male
INTRODUCTION Cryptococcus neoformans commonly affects lungs and central nervous system that to in immunocompromised individual. Bony involvement is extremely rare and most common site is vertebrae and usual presentation is monofocal. CASE REPORT We present 18-year-old male with bifocal osteomyelitis of scapula and tibia in immunocompetent male. CONCLUSION Cryptococcal osteomyelitis should b...
متن کاملIsolated cryptococcal osteomyelitis in an immunocompetent patient.
Cryptococcosis is a rare infection in HIV-negative individuals. While the lungs and the central nervous system are most commonly infected, skeletal cryptococcosis is uncommon and isolated osteomyelitis due to Cryptococcus neoformans is quite rare. To our knowledge, only 47 cases of isolated cryptococcal osteomyelitis have been reported from 1974 to 2005. We report a case of isolated cryptococca...
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ژورنال
عنوان ژورنال: Southern African Journal of Infectious Diseases
سال: 2015
ISSN: 2312-0053,2313-1810
DOI: 10.1080/23120053.2015.1107293